本发明公开了一种医用可降解Zn‑Cu‑Li三元合金及其制备与用途；所述三元合金中Cu元素的质量百分比为1.0～4.0％，Li元素的质量百分比为0.2～1.0％，其余为Zn。本发明涉及的熔炼、挤压或轧制变形及热处理等工艺，可调控该锌合金的微观组织，实现均质化、细晶化和洁净化制备。本发明的锌合金具有优异的力学性能，抗拉强度480～623MPa，拉伸屈服强度447～591MPa，延伸率28～46％，且在室温存储过程中力学性能稳定。体外腐蚀速率为46～78μm/year，呈现均匀腐蚀降解模式。本发明的锌合金无明显的细胞毒性，生物相容性较好，且具有显著的抗菌作用，适合于多种内植入医疗器械的制备，如血管支架、吻合钉、血管夹、骨内植物等。

The invention discloses a medical degradable Zn-Cu-Li ternary alloy and its preparation and use; The mass percentage of Cu in the ternary alloy is 1.0 ~ 4.0%, the mass percentage of Li is 0.2 ~ 1.0%, and the rest is Zn. The melting, extrusion or rolling deformation and heat treatment processes related to the invention can regulate the microstructure of the zinc alloy to achieve homogenization, fine crystallization and clean preparation. The zinc alloy of the invention has excellent mechanical properties, tensile strength 480 ~ 623MPa, tensile yield strength 447 ~ 591MPa, elongation 28 ~ 46%, and stable mechanical properties in the storage process at room temperature. In vitro corrosion rate was 46 ~ 78μm/year, showing uniform corrosion degradation mode. The zinc alloy of the invention has no obvious cytotoxicity, good biocompatibility, and significant antibacterial effect, and is suitable for the preparation of a variety of implantable medical instruments, such as vascular stent, anastomosis nail, vascular clip, bone plant, etc.